Dude. Don’t I know it…
For the New York Times Blog : http://well.blogs.nytimes.com/2013/08/06/how-sleep-loss-adds-to-weight-gain/?_r=0
Dr. Walker said he suspected that one factor that plays a role is a substance called adenosine, a metabolic byproduct that disrupts neural function and promotes sleepiness as it accumulates in the brain. One of the ways that caffeine stimulates wakefulness is by blocking adenosine. Adenosine is also cleared from the system when we sleep.
Without enough rest, adenosine builds up and may start to degrade communication between networks in the brain, Dr. Walker said. Getting sleep may be the equivalent of rebooting the brain.
“I think you have about 16 hours of optimal functioning before the brain needs to go offline and sleep,” he said. “If you go beyond these 16 hours into the realm of sleep deprivation, then those brain networks start to break down and become dysfunctional.”
Dr. Walker said it was increasingly clear from the medical literature that there is not a single tissue in the body that is not beneficially affected by sleep.
“It’s the single most effective thing people can do every day to reset their brain and body health,” he said.